Title

Impact of biofortified maize consumption on serum carotenoid concentrations in Zambian children

Document Type

Article

Publication Date

2018

Abstract

Biofortified maize, designed as an intervention strategy to prevent vitamin A deficiency, can provide upwards of 15 μg β-carotene per g dry weight. Some varieties also have elevated concentrations of other carotenoids. We conducted a cluster randomized, controlled feeding trial in rural Zambia to test the impact of daily consumption of biofortified maize over a 6-month period on vitamin A status. Serum concentrations of retinol and carotenoids were assessed by high-performance liquid chromatography. Data on circulating carotenoids by intervention group in 679 children are reported here. As previously shown, consumption of this β-carotene-rich maize significantly improved serum β-carotene concentrations (0.273 vs. 0.147 μmol/L, p < 0.001, in this subset of children). Here we show significant increases in α-carotene, β-cryptoxanthin, and zeaxanthin (p < 0.001). There was no impact on lutein or lycopene concentrations. Consumption of biofortified maize can have broader implications beyond the control of vitamin A deficiency (Trial registration: NCT01695148).

Recommended Citation

Palmer, Amanda C., Neal E. Craft, Kerry J. Schulze, Maxwell Barffour, Justin Chileshe, Ward Siamusantu, and Keith P. West. "Impact of biofortified maize consumption on serum carotenoid concentrations in Zambian children." European journal of clinical nutrition 72, no. 2 (2018): 301-303.

DOI for the article

10.1038/s41430-017-0054-1

Department

Master of Public Health

Share

COinS