Lipoprotein subfraction changes after continuous or intermittent exercise training
Purpose: This study compared total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) and their respective subfractions after completing 4 wk of either intermittent (INT-EX) or continuous (CON-EX) aerobic exercise training (TRAIN).
Methods: Untrained males (N = 7) and females (N = 11) completed 4 wk of TRAIN of supervised treadmill jogging occurring 5 d·wk-1 for 30 min per session at 60% VO2max (75% HRmax). CON-EX was a single 30-min bout. INT-EX consisted of three 10-min bouts separated by 20 min of seated rest. Pre- and post-TRAIN fasting plasma samples were collected after subjects had followed 48 h of activity restriction and a 24-h repeated diet including a 12-h dietary fast. Postprandial lipemia was measured for 8 h following a standardized high-fat meal.
Results: Fasting triglycerides and very LDL-C were not affected by TRAIN, and TRAIN did not change postprandial area under the curve or peak in either group. With groups combined, TRAIN significantly decreased TC, total LDL-C, and the TC:HDL ratio, and increased HDL-C subfraction 2 and LDL mean particle size. Total intermediate-density lipoprotein cholesterol remained unchanged at post-TRAIN, and was not different between groups.
Conclusions: To prevent dyslipidemia, our findings suggest that persons who are normolipidemic can improve the lipoprotein profile equally with CON-EX and INT-EX by lowered TC through the sum of changes in LDL-C subfractions, increased mean LDL particle size, and increased HDL-C subfraction 2 concentration.
Cholesterol, Exercise fractionization, Normolipidemic, Postprandial lipemia
Altena, Thomas S., Jody L. Michaelson, Steven D. Ball, Brianne L. Guilford, and Tom R. Thomas. "Lipoprotein subfraction changes after continuous or intermittent exercise training." Medicine and science in sports and exercise 38, no. 2 (2006): 367-372.
Medicine and Science in Sports and Exercise