Implication of Yeast Dynamin-Related Protein Vps1 in Endocytosis and Organelle Fission
Dynamin is a multi-domain GTPase found in mammals, which plays an imperative role in fission events at the plasma membrane during endocytosis and membrane-bound internal organelles, including the Golgi membrane (Ramachandran 2011). It has been shown that dynamin and its yeast counterpart, vacuolar protein sorting 1 (Vps1), are highly related proteins sharing similar sequence and function. Through this in-depth review of the literature, we summarize main functions of the dynamic Vps1 protein at diverse locations within the cell.
dynamin, Vps1, endocytosis, Golgi, scission
Brummett, Alexis, Michelle Williams, Jacob Hayden, and Kyoungtae Kim. "Implication of Yeast Dynamin-Related Protein Vps1 in Endocytosis and Organelle Fission." International Journal of Science and Technology 2 no. 1 (2013).
International Journal of Science and Technology