trans-Golgi network-bound cargo traffic
Cargo following the retrograde trafficking are sorted at endosomes to be targeted the trans-Golgi network (TGN), a central receiving organelle. Though molecular requirements and their interaction networks have been somewhat established, complete understanding of the intricate nature of their action mechanisms in every step of the retrograde traffic pathway remains unachieved. This review focuses on elucidating known functions of key regulators, including scission factors at the endosome and tethering/fusion mediators at the receiving dock, TGN, as well as a diverse range of cargo.
cargo, dynamin, endosome, fission, fusion, fusion, tether, trans-Golgi network
Makaraci, Pelin, and Kyoungtae Kim. "trans-Golgi network-bound cargo traffic." European journal of cell biology 97, no. 3 (2018): 137-149.
European Journal of Cell Biology