Homologues of anti-HIV active isodideoxynucleosides
The synthesis of a homologous series of compounds related to the anti-HIV active class of compounds known as (S,S)-isodideoxynucleosides has been completed by a convergent route using a modified carbohydrate intermediate. This precursor, synthesized from d-glucose, was coupled with a variety of natural purine and pyrimidine bases to regiospecifically and stereospecifically afford the desired new class of compounds. © 1995 Elsevier Science Ltd.
anti-HIV, convergent synthesis, homologues, isodideoxynucleosides
Bolon, Pascal; Jahnke, Tamera S.; and Nair, Vasu, "Homologues of anti-HIV active isodideoxynucleosides" (1995). Articles by College of Natural and Applied Sciences Faculty. 2090.