Homologues of anti-HIV active isodideoxynucleosides
The synthesis of a homologous series of compounds related to the anti-HIV active class of compounds known as (S,S)-isodideoxynucleosides has been completed by a convergent route using a modified carbohydrate intermediate. This precursor, synthesized from d-glucose, was coupled with a variety of natural purine and pyrimidine bases to regiospecifically and stereospecifically afford the desired new class of compounds. © 1995 Elsevier Science Ltd.
anti-HIV, convergent synthesis, homologues, isodideoxynucleosides
Bolon, Pascal, Tamera S. Jahnke, and Vasu Nair. "Homologues of anti-HIV active isodideoxynucleosides." Tetrahedron 51, no. 38 (1995): 10443-10452.