Synthesis and conformational studies of new purine isodideoxynucleosides

Lawrence B. Zintek
Tamera S. Jahnke
Vasu Nair

Abstract

The synthesis and NMR conformational correlations (preferred syn or anti) of new isomeric dideoxynucleosides of potential antiviral interest are described. These compounds are related to the potently active anti-HIV compound, (S,S)-isodideoxyadenosine.