New polyethylene glycols for biomedical applications
Polyethylene glycols (PEGs) are water soluble, nontoxic polyethers, the derivatives of which (PEGX) have been used extensively in biomedical applications such as: aqueous two-phase partitioning, protein (i.e. enzyme, antibody, antigen) immobilization, drug modifications, and the preparation of surfaces that reject proteins. The authors report syntheses of PEG derivatives by both methods and illustrate their attachment to surfaces and to proteins.
Harris, J. Milton, Julian M. Dust, R. Andrew McGill, Patricia A. Harris, Michael J. Edgell, Reza M. Sedaghat-Herati, Laurel J. Karr, and Donna L. Donnelly. "New polyethylene glycols for biomedical applications." 1991.
American Chemical Society, Polymer Preprints, Division of Polymer Chemistry