Extrapolation from small molecules to polymers: A simple and effective way to promote interest in both organic chemistry and polymer chemistry
Two methods to integrate polymer chemistry within the regular organic chemistry curriculum are presented. The first method extrapolates small molecule synthetic methodology to the synthesis of polymers. For example, the common organic reaction, Fischer esterification, is extended to the synthesis of diesters and polyesters. This approach is also used to introduce polyamides. The second method relies on a clear understanding of reaction mechanism in order to divert a small molecule synthesis to the synthesis of a polymer. Examples include extrapolation from the base-catalyzed hydrolysis of epoxides to the synthesis of polyethyleneglycol and extrapolation from conjugate addition to superglue. © 2013 American Chemical Society.
Bosch, Eric. "Extrapolation from Small Molecules to Polymers: A Simple and Effective Way To Promote Interest in Both Organic Chemistry and Polymer Chemistry." In Introduction of Macromolecular Science/Polymeric Materials into the Foundational Course in Organic Chemistry, pp. 53-62. American Chemical Society, 2013.
ACS Symposium Series