Design and Synthesis of C2-Symmetric N-Heterocyclic Carbene Precursors and Metal Carbenoids
Chiral, C2-symmetric imidazolium and imidazolinium ions, as well as the corresponding copper- or silver-bound carbenoids, have been prepared. Structural study of these compounds by X-ray crystallography reveals a chiral pocket that surrounds the putative carbene site or the metal–carbene bond, at carbon 2, in three of the four ligands prepared. Preliminary investigation into the application of these complexes has shown one of them to be highly enantioselective in the hydrosilylation of acetophenone.
imidazolium, copper, metals, crystal structure, hydrosilylation
Albright, Abigail, Daniel Eddings, Regina Black, Christopher J. Welch, Nikolay N. Gerasimchuk, and Robert E. Gawley. "Design and synthesis of C2-symmetric N-heterocyclic carbene precursors and metal carbenoids." The Journal of organic chemistry 76, no. 18 (2011): 7341-7351.
The Journal of organic chemistry