Motexafin gadolinium reacts with ascorbate to produce reactive oxygen species

Abstract

Motexafin gadolinium (MGd) oxidizes ascorbate, in neutral buffer and in cell culture, forming reactive oxygen species and a coordination polymer with oxalate.

Department(s)

Chemistry and Biochemistry

Document Type

Article

DOI

https://doi.org/10.1039/b208760j

Publication Date

2002

Journal Title

Chemical communications

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