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Theses from 2023

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Tissue and Sex-Dependent Regulation of Innate Immunity and RNA Editing in Mice, Kelsey R. Kendrick

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Sex-Dependent Effects of Induced Acute Inflammation on Glucose Homeostasis and RNA Editing Enzymes, Christian A. Rivas

Theses from 2022

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Further Investigation of the Initiating Mechanism of the Type I Collagen Glomerulopathy, Matthew James Freese

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The Role of the Host Factor SPTBN1 in HIV-1 Infection of Microglial Cells, Marc Gordon Havlicek

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The Role of Actin Associated SPTBN1 Host Factor in HIV-1 Infection in Microglial Cells, Hannah Matheney

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Tissue and Sex-Specific RNA Editing During Induced Acute Inflammation, Claire E. Nichols

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Effectiveness of Stabilized Hypochlorous Acid in Acute Peritonitis Treatment: A Murine Surgical Study, Benjamin Michael Pomeroy

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A Study of Cobalt (III) Oxide Nanoparticle Delivery of siRNA Molecules Directed Against Signaling Intermediates of the P2Y2 Receptor, Rachel Blair Stroud

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Role of Cyclophilin A and TRIM5α in HIV-1 Infection and Capsid Uncoating, Emma LK Wise

Theses from 2021

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The Effect of the Interaction of Exercise Training and Isolation on the Serotonergic System of App/Ps1 Mice, Bailey J. Dansby

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Exercise Training Rescues Increased Brain ISF aβ Caused by Chronic Isolation Stress in APP/PS1 Transgenic Mice, Lydia M. Holtmann

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Modulation of Glucose Homeostasis by Nucleotide P2Y2 Receptor and Biological Sex, Hailee Anne Marino

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Neuronal Migration in Developmental Hyperserotonmia: Assessment of Vesicular Glutamate in the Raphe Nuclei, Trey M. Shupp

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Nucleotide P2y₂ Receptor-Dependent Leukocyte-Endothelial Interaction, Spencer E. Thomas

Theses from 2020

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The Role of RNA Editing Within Calcium-dependent Activator for Secretion 1 in Large Dense Core Vesicle Fusion, Kaylee M. Mathiason

Myosin V-Mediated Cargo Traffic toward the Trans-Golgi Network and Myosin v Implications in Snc1 Exocytosis, Vy Ngoc Khanh Nguyen

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A Novel UV Resistance in Rad23-Depleted Tetrahymena thermophila, Emily M. Schmoll

Theses from 2019

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Assessment of Motor Function, Motor Learning, & Olivary Climbing Fiber Distribution within Developmental Hyperserotonemia Rat Model for Autism Spectrum Disorder, Elizabeth Diane Holland

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Cyclophilin A Enhances HIV-1 Reverse Transcription in Human Microglial Cells, Zachary Michael Ingram

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Further Characterization of the Skeletal Phenotype in a Hurler Syndrome Mouse Model and the Ethical Treatment of Children in Medicine, Anna Marie McWoods

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Kinetics of HIV-1 Uncoating in C20 Microglial Cells, Melanie Anne Taylor

Theses from 2018

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Investigation of the Homologs Rad51 and Dmc1 Role in Cell Division and Homologous Recombination, Amaal Abulibdeh

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The Role of RAD4 in DNA Repair and Its Interplay with Telomeres in Tetrahymena thermophila, Emily Nischwitz

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Investigation into the Role of Platelet Derived Growth Factor (PDGF) in Type I Collagen Glomerulopathy, Isaac C. Springer

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The Effects Of Long-Term Treadmill Exercise Training On Amyloid-Beta Plaque Levels and Behavioral Profile in 15-Month Tg2576 Mice, Riya R. Thomas

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Development of Endogenous Tagging Plasmids for Characterization of Protein Interactions, Localization, and Post-Translational Modifications of Tetrahymena Thermophila Rad23, Evan Andrew Wilson

Theses from 2016

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A Biologically Active Tnf-Alpha Inhibitor Fails To Suppress Colitis In Balb/C Mice, Stephanie E. Biel

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Identification And Characterization Of DNA Repair Snf2/Swi2 Atpases In Tetrahymena Thermophila, Andrew Francis Morin

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Characterization Of The Skeletal Phenotype In Idua-W392X Knock-In Mice: Bone Metabolism Biomarkers, Christina J. Owensby

Theses from 2015

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Systemic Insulin Sensitivity and Skeletal Muscle Akt Signaling in Rats Artificially Selected for Low and High Aerobic Capacity, Kyle Levi Fulghum

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Tumor Necrosis Factor Alpha Converting Enzyme Inhibition during Acute Colitis in Mice: A Regional Analysis, Brian Maddox

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Sirt2 & Sirt3 in Cancer & Aging, and Characterization of Their Homologs THD13, 15, & 16 in Tetrahymena Thermophila, Micheala Alexis Jordan Steinmetz

Theses from 2014

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Characterization of the Chromatin Modifying Proteins GCN5, ESA1, and CHD1 and Their Alternative Roles in Tetrahymena Thermophila, Lynn Ann Andreas

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Characterization of Four Tetrahymena Thermophila SIRT6 Histone Deacetylase Homologs and Their Response to Genotoxic Stress, Sean William Burk

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Splice Switching Oligonucleotides: Model System Characterization, Nanomaterial Delivery, and Rational Design for Targeting Melanoma at the RNAa Level, John Michael Dean

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The Effect of Age on Running Economy in a Mouse Model of Alzheimer's Disease, Monica Nicole Goodland

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Modulation of Microvascular Barrier Property By the P2Y2 Receptor: the Role of Focal Adhesion Kinase, Joseph David Harvey

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Adiponectin Expression in Murine Colitis Following TNF- Converting Enzyme Inhibition, Tricia Anne Haynes

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Differential Methylation of Sonic Hedgehog Pathway Genes in Acute Lymphoblastic Leukemia, Dallas S. Massey

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Insight Into the Multifunctional Adaptor Protein β-Arrestin, Katie Deann McLemore

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Dose-Response Relationship Between Exercise Training and Soluble Aβ and Associated Clearance Protein Levels in Young Adult Tg2576 Mice, Kaitlin Maureen Moore

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Comparative Characterization of Pre-Clinical Anti-Cancer RNA Nanoconjugate Candidates, Ashley Marguerite Schaeffer

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Modulation of VE-Cadherin in Response to UTP Stimulation in HUVEC, Aparna Tiwari

Theses from 2013

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Assessing DNA Damage and Repair in Various Chromatin States in Tetrahymena Thermophila, Steven Anton Hill

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Characterization of Tetrahymena Histone Deacetylase 13 and 15, Sirt3 Homologs That Change Expression in Response to Genotoxic Stressors, Christopher Allen Huxel

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Effects of Six Months of Treadmill Running on Amyloid Beta, Plaque Load, and Behavior in TG2576 Mice, Whitney Lauren Schroer

Theses from 2012

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Characterizing the Role of Tetrahymena Histone Deacetylase 2 in DNA Damage Repair in the Ciliate Tetrahymena Thermophila, Kailey Deane Barron

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Tetrahymena Histone Deacetylase 14, a Stress-Responsive Class I Sirtuin That Changes Localization and Expression in Response to Genotoxic and Metabolic Stress, Kyle Aaron Cottrell

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The Role of Disruption of Meiotic Control 1 (DMC1) in DNA Repair in Tetrahymena Thermophila, Allie Kay Maltzman

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Characterization of Novel Nanocomplexes Derived from Cobalt Hexamine, Polyacrylic Acid and RNA, Sindhuri Venuturumilli

Theses from 2011

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Fibrinogen Gamma' Inhibits Thrombin-Induced Platelet Activation, Amruta Ashtekar

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Anti-Sense Oligonucleotide Mediated Inhibition of the Murine P2Y2 Receptor Desensitization Mechanism, Lucas Harmon Bradley

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The Effects Of Exercise Intensity On Young Alzheimer's Disease Mice Living In Enriched Environments, Renee N. Ehrenstrom

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Characterization of Distinct Sequential Subsets of IL-10 Induced Genes in LPS-Triggered Human Monocytic Cells, Brad Groppe

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Qualification of Telomeric Maintenance and Elongation Due to Pulsed Electromagnetic Resonance Exposure, Scott C. Kelsey

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The Role of DNA Damage Dependent Rad23 Ubiquination in Stabilization of Rad4, Archana none Shrestha

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Identification and Characterization of Histone Deacetylase 11 in Tetrahymena Thermophila, Steven Craig Snyder

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Biophysical Characteristics of a Zinc Oxide-Based Nanoseries: Interactions with Proteins and Effects on Human Cancer Cells, Laurie Lee Washington

Theses from 2010

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Development of C. Elegans Axenic Culture and RNAi Reagents for Testing Single-Walled Carbon Nanotubes as a Delivery System for RNA, Lala Shashmi Jaiswal

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Detection of Collagen Type I Promoter Activity: Method Development, Shelley Ann Lietzau Mourer

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Potential for Novel Nucleic Acid Delivery Agents: Binding of Macromolecular RNA onto MnO Nanorods Mediated by PAMAM, Brooke Danielle Parker

Theses from 2009

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The Effects of Voluntary and Forced Exercise on Memory, Plaque Deposition, and Hippocampal Volume in the Tg2576 Mouse Model of Alzheimer's Disease, Matthew Jon Kling

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The Effect of C-Terminal Alterations of the P2Y2 Receptor on Calcium Signaling and Desensitization, Amy Katherine Schiller

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Expression of an N-Terminus GFP Tagged P2Y2 Receptor in 1321N1 Human Astrocytoma Cells, Raja Virendhra Bharath Thotakura

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Synthesis of the gfp-tat Fusion Protein For Analysis of the Tat Cell Penetrating Peptide, Chad Michael Walesky

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Sequencing and Annotation of Potential Cis-Acting Transcription Elements in the Emb-9 Gene Promoter of Caenorhabditis Elegans, Joseph P. Williams

Theses from 2008

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Effects of Age and Exercise on Collagen Type I Gene Promoter Activity, Ashely Ann Anderson

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Characterization of Actin Filament Organization in Muscle Cells of C. Elegans Collagen Iv Mutants, Hinda Doucoure

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The Effect of Extracellular ATP, 2MeSTAP, And ATP[Gamma]S On MDA-MB-231 Breast Cancer Cells In The Presence Of Extracellular Calcium, Caleb Masterson

Theses from 2007

Engineering of a Collagen IV::Gfp Fusion Protein Using Polymerase Chain Reaction, Courtney Elizabeth Eaves

Age Attenuated Cutaneous Vasoconstrictor Response to Norepinephrine Is Apparent with Bretylium Tosylate, Daniel Skirrow Short

Theses from 2006

Identification and Analysis of a Putative Cell Surface Receptor For C. Elegans Collagen Type IV Using Bioinformatics Tools and RNA Interference Mechanism, Srilatha Nalluri

Intracellular Trafficking Of Connexin 43 (Cx43) And Gap Junction Formation In Leiomyosarcoma Cells Following Interruption With Brefeldin A And Cycloheximide, Tammy S. Welchert

Theses from 2005

Characterization and Identification of Putative Collagen Iv Cell Surface Receptors in C. Elegans Through the Utilization of RNA Interference and Bioinformatics, Shannon M. Burcks

The Internet's Impact on Journalism, Paula J. Smith

The Effect of Protein Kinase C Inhibitors on Desensitization of the Murine P2Y2 Receptor, Dana K. Tucker

Theses from 2004

The Effect Of C-Terminal Tail Mutations On Desensitization Of The Murine P2Y2‚ Nucleotide Receptor, Hillary M. Glauser

Integrin Distribution in Collagen Iv Mutants and Use of Rna Interference to Identify a Collagen Iv Receptor in C. Elegans, Umme Rumana

Production Of A Functional Collagen Type IV:: GFP Fusion Protein Reporter Construct In Caenorhabditis Elegans, David K. Stone

Theses from 2003

Effect of Emb-9 and Let-2 Mutations on the Proper Assembly of Basement Membranes and on the Morphology of Body Wall Muscle Cells in Caenorhabditis Elegans, Libia Chandler

Analysis of a Proposed Cell Binding Site on Caenorhabditis Elegans Collagen Type Iv, Lori G. Langiano