Date of Graduation

Spring 2013


Master of Science in Communication Sciences and Disorders


Communication Sciences and Disorders

Committee Chair

Klaas Bakker


aphasia, electrophysiology, P300, oddball, stimulation

Subject Categories

Communication Sciences and Disorders


This was an exploratory study that focused on measuring the P300 event related potential to determine changes in neurophysiological activity when subjects were presented with multi-modal sensory stimulation (auditory and visual) compared to uni-modal sensory stimulation (auditory only). Subjects were presented with auditory oddball paradigms. Activity was measured at multiple sites (Fz, Cz, and Pz) consistent with suggestions from electrophysiological research. Two adults with a diagnosis of aphasia were the subjects. The research question focused on how the presence of multi-modal sensory stimulation changed the latency, amplitude of the P300 response. Behavioral outcomes were also quantified. Results showed an overall increase in P300 amplitude at all sites in both participants. These results indicate possible changes in outlook for treatment in aphasia therapy. Further research in to this area is warranted to draw more conclusive results.


© Allison Michelle Becker

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