Thesis Title
Synthesis of Furan-Based Poly(Ethylene Glycol) Derivatives and Their Diels-Alder Reactions
Date of Graduation
Summer 2001
Degree
Master of Science in Chemistry
Department
Chemistery
Committee Chair
Reza Herati
Subject Categories
Chemistry
Abstract
Poly (ethylene glycol) (PEG) and its derivatives exhibit many useful properties, which have led to a vast array of biomedical and biotechnical applications. Several PEG derivatives have been prepared for use in these applications. However, there is a continuous interest in new PEG derivatives that are easily prepared and possess useful properties. In this work, we have synthesized two new furan-based PEG derivatives namely, 2-[methoxypoly(oxyethylene) furan and 3-[methoxypoly(oxyethylene)methylene]furan. The Diels-Alder reactions of the above derivatives with maleic anhydride, N-phenylmaleimide, N-2-mehylphenylmaleimide, maleimide, and diethylacetylene dicarboxylate have been investigated. The products of these reactions have been characterized by spectroscopic techniques such as ¹H NMR, ¹³C NMR and IR. In addition, aromatization of the Diels-Alder adducts obtained from the reaction of 5-[methoxypoly(oxyethylene)]-(3E)-1, 3 pentadiene amd 5-methoxyethoxy-(3E)-1, 3-pentadiene with diethylacetylene dicarboxylate by DDQ has been achieved, and these products have also been characterized by spectroscopic techniques.
Copyright
© Almary Chacon
Recommended Citation
Chacon, Almary, "Synthesis of Furan-Based Poly(Ethylene Glycol) Derivatives and Their Diels-Alder Reactions" (2001). MSU Graduate Theses. 2400.
https://bearworks.missouristate.edu/theses/2400
Dissertation/Thesis
