Thesis Title

Antigenic Variation in Candida Albicans

Author

Jana Podzimek

Date of Graduation

Summer 1980

Degree

Master of Science in Biology

Department

Biology

Committee Chair

Richard Myers

Subject Categories

Biology

Abstract

The antigenicity of the germ tube and the yeast phase of Candida albicans have been compared by crossed immunoelectrophoresis, tandem-crossed immunoelectrophoresis and classical immunoelectrophoresis. Qualitative and quantitative differences between the two growth forms have been observed. One unique antigen to the yeast phase was found. Possible roles of phase-specific antigens in the study of pathogenicity of C. Albicans are discussed. The crossed immunoelectrophoresis technique proved to be a more sensitive method for antigenic studies than classical immunoelectrophoresis.

Copyright

© Jana Podzimek

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Dissertation/Thesis

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