Frequency dependent hysteresis of silicone and latex mock arteries used in stent testing
Mock arteries also called as mock vessels are one of the best alternatives available to researchers in evaluating the mechanical characteristics and durability of intravascular medical products without having to use animal and human clinical studies. The behavior of mock arteries depends on the frequency of loading. This makes it essential to evaluate and analyze the compliance and hysteresis of the mock arteries at different frequencies. Hysteresis, the difference in the pressure-volume curve between the loading cycle and the unloading cycle, plays an important role in determining the mechanical properties of the mock arteries. Six each of silicone and latex mock arteries were tested for this study. Three silicone and three latex mock arteries were tested at room temperature for dynamic internal compliance, and the remaining three each of silicone and latex mock arteries were soaked in distilled water at 37° C for 36 hours and then compliance tested using a dynamic compliance tester. All arteries were tested at four different frequencies: 72, 500, 1000, and 1500 beats per minute. Results showed that as the frequency is increased, the area of the hysteresis curve increased and the compliance of the tube decreased. This was clearly evident in both silicone and latex mock arteries. Latex mock arteries had more hysteresis compared to silicone mock arteries. The compliance of only the latex mock arteries was affected by soaking in distilled water; the compliance of silicone mock arteries did not change. Latex mock arteries showed higher compliance than silicone mock arteries in either the soaked or unsoaked condition.
Physics, Astronomy, and Materials Science
Artery, Compliance, Frequency, Hysteresis, Latex, Silicone, Stent, Testing, Vessels
Ramesh, R., E. Strope, K. Price, and J. C. Conti. "Frequency dependent hysteresis of silicone and latex mock arteries used in stent testing." Biomed Sci Instrument 41 (2005): 163-168.
Biomedical Sciences Instrumentation