Synthesis Of Poly(Ethylene Glycol) Vinyl Ethers And Their Copolymerization With N-Phenylmaleimide
Date of Graduation
Master of Science in Chemistry
The applications of methoxy poly(ethylene glycol) (MPEG) and its derivatives are diverse and are important in biomedical, analytical, cosmetic, and pharmaceutical industries. A new method for the synthesis of methoxytriethylene glycol vinyl ether (1a) and methoxyoly (ethylene glycol) with average molecular weights of 820 and 2070 daltons (2a) has been developed which is simple, easily purified, and operates at ambient temperature. The products of these reactions have been verified by spectroscopic techniques. In addition, 1a and 2a were copolymerized with N-Phenylmaleimide (NPHMA) by free-radical addition to form alternating copolymers of nearly one-to-one mole composition. Copolymer composition was verified by ¹H-NMR and by charting reaction efficiency at various monomer feeds. Copolymer molecular weight distributions were verified by gel permeation chromatograpahy (GPC).
© Michael Tyndall
Tyndall, Michael, "Synthesis Of Poly(Ethylene Glycol) Vinyl Ethers And Their Copolymerization With N-Phenylmaleimide" (2002). MSU Graduate Theses. 1864.