Date of Graduation
Master of Science in Chemistry
pyridine, ligand, silver, proton, NMR, nuclear magnetic resonance, binding constant
Ligands based on the known ligand 1,2-bis(2'-pyridylethynyl)benzene, which is known to selectively bind to silver(I), were synthesized. To accomplish improved binding of silver(I), one or two side arms were attached to one of the pyridine rings on the ligand. Each side arm contained either an oxygen or nitrogen, which provides an extra "tooth” to bind to silver(I). The binding constants of the ligands to silver(I) were determined using 1H NMR spectroscopy. A silver solution was titrated into a ligand solution in DMSO-d6 at millimolar concentrations. The binding constants were calculated in two ways using the NMR titration data. The data showed the ligand with a single nitrogen containing side arm had the strongest binding to silver(I), followed by the ligand with two nitrogen containing side arms. Both of these ligands showed stronger binding to silver(I) than the unsubstituted bypyridyl ligand. The ligand with a single oxygen containing side arm showed decreased binding strength as compared to the unsubstituted bipyridyl ligand.
© Lauren R. Verheyen
Verheyen, Lauren R., "Synthesis of New Tridentate and Tetradentate Ligands to Complex Silver(I)" (2012). MSU Graduate Theses. 1984.