Date of Graduation
Master of Science in Materials Science
Physics, Astronomy, and Materials Science
core-shell nanoparticles, biocompatibility, carbon, cobalt ferrite, ferromagneism, Raman spectroscopy, fluorescence, transmission electron microscopy
Nanoscience and Nanotechnology
Considerable research work is going on worldwide among the therapeutic scientific communities to use magnetic nanoparticles (NPs) as a controlled drug delivery system. Challenges to use those NPs for such in-vivo applications successfully are mainly biocompatibility and the functionality of those NPs. Addressing the needs, in this project, we synthesized carbon-coated cobalt ferrite (CFO) core-shell nanoparticles (CSNPS) by ablating a solution of toluene and CFO NPs with varying number of pulsed laser shots. The structure of the CSNPs then investigated through X-ray diffraction (XRD), Raman spectroscopy, and also with the high-resolution transmission electron microscopy (HRTEM). The XRD analysis shows that the inner structure of CFO remains intact after the laser ablation. The Raman data analysis confirmed that with increasing laser shots the amount of crystallinity of the carbon structure increases and the G-band peak becomes more prominent which infers fewer defects in the shell structure. The TEM images showed that the carbon is mostly present in the shell region and the intensity count from the line scan data concludes the formation of the core-shell structure of CFO NPs. Thus, the laser ablation technique turned out quite efficient to manufacture carbon-coated magnetic metal oxide CSNPs for further applications. To increase the functionality of the NPs, nitrogen was then introduced in the shell region using N, N-DMF solution along with toluene. Fluorescence spectroscopy of these two different types of coatings indicates subtle changes in the higher wavelength region, and SEM analysis informs the presence of nitrogen in the NPs although the future study is needed to confirm the existence of nitrogen in the shell structure of CFO CSNPs.
© Joy Roy
Roy, Joy, "Fabrication of Multifunctional Carbon Coated Cobalt Ferrite Core/Shell Nanostructures by Pulsed Laser Ablation" (2020). MSU Graduate Theses. 3540.