Title
Efficacy of bupropion alone and in combination with nicotine gum
Abstract
In this double-blind, placebo-controlled smoking cessation treatment study, 608 participants were randomly assigned to receive active bupropion and active 4-mg gum (AA, n=228), active bupropion and placebo gum (AP, n=224), or placebo bupropion and placebo gum (PP, n=156). Relative to the PP group, the AA and AP groups were each significantly more likely to be abstinent at 1 week, end of treatment, and 6 months but not at 12 months postquit. After the first week postquit there were no differences in abstinence rates between the AA and AP groups. We found no significant individual difference variables that moderated outcome beyond 1 week postquit.
Department(s)
Master of Public Health
Document Type
Article
DOI
https://doi.org/10.1080/14622200701540820
Keywords
nicotine chewing gum, bupropion, smoking cessation
Publication Date
2007
Recommended Citation
Piper, Megan E., E. Belle Federman, Danielle E. McCarthy, Daniel M. Bolt, Stevens S. Smith, Michael C. Fiore, and Timothy B. Baker. "Efficacy of bupropion alone and in combination with nicotine gum." Nicotine & Tobacco Research 9, no. 9 (2007): 947-954.
Journal Title
Nicotine & Tobacco Research
