New polyethylene glycols for biomedical applications

Authors

J. Milton Harris
Julian M. Dust
Reza Sedaghat-Herati Sedaghat-HeratiFollow
R. Andrew McGill
Cindy Upton

Abstract

Polyethylene glycols (PEGs) are water soluble, nontoxic polyethers, the derivatives of which (PEGX) have been used extensively in biomedical applications such as: aqueous two-phase partitioning, protein (i.e. enzyme, antibody, antigen) immobilization, drug modifications, and the preparation of surfaces that reject proteins. The authors report syntheses of PEG derivatives by both methods and illustrate their attachment to surfaces and to proteins.

Document Type

Conference Proceeding

DOI

https://doi.org/10.1021/bk-1991-0467.ch027

Publication Date

9-1-1989

Recommended Citation

Harris, J. Milton, Julian M. Dust, R. Andrew McGill, Patricia A. Harris, Michael J. Edgell, Reza M. Sedaghat-Herati, Laurel J. Karr, and Donna L. Donnelly. "New polyethylene glycols for biomedical applications." 1991.

Journal Title

American Chemical Society, Polymer Preprints, Division of Polymer Chemistry