Preparation of 2′-aminoacetophenones: A one-pot hydration and reduction of 1-ethynyl-2-nitrobenzenes

Abstract

The reductive hydration of 1-ethynyl-2-nitrobenzenes to the corresponding 2′-aminoacetophenones with a range of common reducing agents is described.

Department(s)

Chemistry and Biochemistry

Document Type

Article

DOI

https://doi.org/10.1016/S0040-4039(01)01758-0

Publication Date

11-12-2001

Journal Title

Tetrahedron Letters

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