Desilylation of α-trimethylsilylmethylene-δ-lactones. A new route to α-methylene-δ-lactones

Authors

Mario D. Bachi
Eric BoschFollow

Abstract

Addition of phenylthiol to α-trimethylsilylmethylene-δ-lactones affords α-phenylthi(trimethylsilyl)methyl-δ-lactones which, on treatment with tetrabutyl-ammonium fluoride and methyl acrylate give the corresponding α-methylene-δ-lactones through a one-pot double deblocking process.

Document Type

Article

DOI

https://doi.org/10.1016/S0040-4039(00)86117-1

Publication Date

1-1-1988

Recommended Citation

Bachi, Mario D., and Eric Bosch. "Desilylation of α-trimethylsilylmethylene-δ-lactones. A new route to α-methylene-δ-lactones." Tetrahedron letters 29, no. 21 (1988): 2581-2584.

Journal Title

Tetrahedron Letters