Diels-Alder Reactions of 5-[Methoxypoly(Oxyethylene)]-(3E)-1,3-Pentadiene

Author

Timothy Edward Hopkins

Date of Graduation

Fall 1999

Degree

Master of Science in Chemistry

Department

Chemistry and Biochemistry

Committee Chair

Reza Herati

Abstract

Poly(ethylene glycol) (PEG) derivatives have wide utility for a variety of biomedical and biotechnical applications, and interest continues in the synthesis of new PEG derivatives that possess novel properties. In this work, we have performed the synthesis of 5-[methoxypoly(oxyethylene)]-(3E)-1,3-pentadiene (Ia) and 5-methoxyethoxy-(3E)-1,3-pentadiene (Ib). Diels-Alder reactions of Ia and Ib with acrolein, maleic anhydride, and diethyl acetylenedicarboxylate have been performed. The products of these reactions have been analyzed by spectroscopic techniques. The Diels-Alder adducts of Ia with maleic anhydride and acrolein are converted corresponding N-hydroxysuccinamide esters. Hydrolysis of these esters have been studied, and their hydrolysis reactions have been investigated.

Subject Categories

Chemistry

Copyright

© Timothy Edward Hopkins

Recommended Citation

Hopkins, Timothy Edward, "Diels-Alder Reactions of 5-[Methoxypoly(Oxyethylene)]-(3E)-1,3-Pentadiene" (1999). MSU Graduate Theses. 348.
https://bearworks.missouristate.edu/theses/348